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Jurnal Ilmiah

The Effect of Cyperus Rotundus on Memory and the Number of Hippocampus Cells on Alcohol Administration

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Background: Cyperus rotundus is a type of weed plant difficult to eradicate that has been popular as a traditional medicine in the traditional Asian medicine.
The Objective: This study was conducted to see if Cyperus rotundus could prevent a decrease in the number of pyramidal hippocampal cells in mice due to ethanol administration.
Method: Twenty-five male Spinoque-Dowley rats aged 30 days were divided into five groups were given mineral water, 25% alcohol, the ethanol extract of C.rotundus tuber with doses of 0.325, 0.75 and 2.5gr. Morris water maze testing performed on the first, second, third, tenth and seventh day of treatments. The rats are euthanasia with transcardial perfusion to take the hippocampus. Calculation of hippocampal cells is done by stereology.
Result: From the Morris water maze test of hippocampal cell counting there were significant differences between groups. The highest number of hippocampus cells in the sequence are: Group 1, Group 4 and the smallest is Group 2. Similarly, Morris water maze test results of the fastest time in series are Groups 1, 4, 3, 5 and the longest 2. This condition suggests that ethanol decreases the number of hippocampal cells and decreases memory function. Also, C. rotundus has been shown to prevent a reduction in the number of hippocampal cells and avoid the decline in memory function.
Conclusion: Ethanol causes a decrease in the number of hippocampal cells and decreased memory function, and C. rotundus can prevent a reduction in the number of hippocampal cells and decreased memory function.


Informasi Detail

Pernyataan Tanggungjawab
Pengarang
Munjiati - Pengarang Utama
Shobirun - Pengarang Tambahan
Heru Supriyatno - Pengarang Tambahan
Ronal Tolkhah - Pengarang Tambahan
Supriyadi, - Pengarang Tambahan
NIM
Bahasa
Indonesia
Deskripsi Fisik
PP 15-17
Dilihat sebanyak
298
Penerbit ARC Publication : Amerika.,
Edisi
Volume 3, Issue 2, 2017,
Subjek
Klasifikasi
070

Lampiran Berkas

Citation
Munjiati. (2017).The Effect of Cyperus Rotundus on Memory and the Number of Hippocampus Cells on Alcohol Administration(Volume 3, Issue 2, 2017,).Amerika:ARC Publication

Munjiati.The Effect of Cyperus Rotundus on Memory and the Number of Hippocampus Cells on Alcohol Administration(Volume 3, Issue 2, 2017,).Amerika:ARC Publication,2017.Jurnal Ilmiah

Munjiati.The Effect of Cyperus Rotundus on Memory and the Number of Hippocampus Cells on Alcohol Administration(Volume 3, Issue 2, 2017,).Amerika:ARC Publication,2017.Jurnal Ilmiah

Munjiati.The Effect of Cyperus Rotundus on Memory and the Number of Hippocampus Cells on Alcohol Administration(Volume 3, Issue 2, 2017,).Amerika:ARC Publication,2017.Jurnal Ilmiah



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